Fertility&Endometriosis
Inflammation in the Body Can Damage Sperm
In women with endometriosis, inflammation can create obstacles for fertility. Substances like TNF-α and immune cells called macrophages gather in the abdominal fluid. These can damage sperm by breaking their DNA, which is their genetic blueprint. They can also interfere with how well sperm can move and perform the vital acrosome reaction needed to fertilise an egg.
In women with endometriosis, inflammation can create obstacles for fertility. Substances like TNF-α and immune cells called macrophages gather in the abdominal fluid. These can damage sperm by breaking their DNA, which is their genetic blueprint. They can also interfere with how well sperm can move and perform the vital acrosome reaction needed to fertilise an egg.
Sperm’s Journey to the Egg Is Made More Difficult
Endometriosis can also affect the lining inside the fallopian tubes. This can make it harder for sperm to find their way and reach the egg. When sperm can’t get through easily, chances of fertilisation decrease. We understand how upsetting this can be, but please know that help is available.
Endometriosis can also affect the lining inside the fallopian tubes. This can make it harder for sperm to find their way and reach the egg. When sperm can’t get through easily, chances of fertilisation decrease. We understand how upsetting this can be, but please know that help is available.
Tiny Particles in Vaginal Secretions Can Harm Sperm
Women with endometriosis sometimes have small particles called extracellular vesicles (EVs) in their vaginal secretions. These EVs can directly harm sperm by slowing them down and reducing their ability to fertilise the egg. They can even increase inflammation, making it even harder for conception to happen.
Women with endometriosis sometimes have small particles called extracellular vesicles (EVs) in their vaginal secretions. These EVs can directly harm sperm by slowing them down and reducing their ability to fertilise the egg. They can even increase inflammation, making it even harder for conception to happen.
Oxidative Stress Can Damage Sperm
Within the reproductive system, harmful molecules called reactive oxygen species (ROS) can attack sperm cells. This can damage their outer membrane and energy-producing parts called mitochondria. As a result, sperm may become less mobile and more prone to genetic problems, both of which are vital for successful fertilisation.
Within the reproductive system, harmful molecules called reactive oxygen species (ROS) can attack sperm cells. This can damage their outer membrane and energy-producing parts called mitochondria. As a result, sperm may become less mobile and more prone to genetic problems, both of which are vital for successful fertilisation.
© 2025 by The Vita Pro Berestara Ltd All rights reserved.
Privacy Policy
Terms of Use
Legal Notice
Note/Disclaimer: (1) The information provided on this website is for educational purposes only and is not intended to serve as medical advice. Please do not apply any of this information without first speaking with your doctor. (2) Statements not evaluated by the FDA, not intended to diagnose, treat, cure or prevent any disease.
Designed By: Dr Ksenia Alex
Privacy Policy
Terms of Use
Legal Notice
Note/Disclaimer: (1) The information provided on this website is for educational purposes only and is not intended to serve as medical advice. Please do not apply any of this information without first speaking with your doctor. (2) Statements not evaluated by the FDA, not intended to diagnose, treat, cure or prevent any disease.
Designed By: Dr Ksenia Alex